汪盛　副教授　生物物理　研究领域面向重要生理功能的生物大分子，结合结构生物学（包括：X射线结晶学、核磁共振以及计算生物学）以及生物、化学表征分析手段，系统且前瞻性研究靶标大分子与其配基相互作用，并利用分子设计学进行优化改造，开发具有潜在应用价值的候选物，并为临床诊治提供理论指导

学习和工作经历
1993/09 –1997/07，西南师范大学，化学化工学院，本科
1997/09 –2000/06，中科院福建物构所，硕士（导师：庄鸿辉）
2000/09 –2004/01，重庆大学和中科院国家微重力室联培，博士（导师：蔡绍皙，王大成）
2004/04 –2006/06，中科院国家微重力室，博士后（合作导师：胡文瑞，王大成）
2006/06 – 至今，华中科技大学，生命科学与技术学院，副教授

主持及参与的科研项目
先后参与了973、863计划等重大科研项目，主持过教育部、总装备部，湖北省、广东省等省部级项目

代表性文章
1 Guan XingLei, Wu PengFei, Wang Sheng, Zhang JuanJuan, Shen ZuCheng, Luo Han, Chen Hao, Long LiHong, Chen JianGuo, Wang Fang. Dimethyl sulfide protects against oxidative stress and extends lifespan via a methionine sulfoxide reductase A-dependent catalytic mechanism. Aging Cell, 2016, pp1-11. doi: 10.1111/acel.12546. [Epub ahead of print]
2 Feng Han, Sheng Wang, Ling Guo, Aviansh S. Punekar, Rudolf Ladenstein, Da-Cheng Wang and Wei Liu. MD simulation of crystal structures reveals post-translational modification dependent conformational changes in heat shock factor - DNA interaction. Protein Cell, 2016. DOI 10.1007/s13238-016-0331-0.
3 Chun Zhang,* Zhen Wang, Liangxiao Tan, Tian-Long Zhai, Sheng Wang,* Bien Tan,* Yan-Song Zheng,* Xiang-Liang Yang, and Hui-Bi Xu. A Porous Tricyclooxacalixarene Cage Based on Tetraphenylethylene. Angew Chem Int Ed, 54, 2015: 9244 –9248.
4 Tianfu Cai,Ji Luo, Er Meng, Jiuping Ding, Songping Liang, Sheng Wang, Zhonghua Liu. Mapping the interaction site for the tarantula toxin hainantoxin-IV (-TRTX-Hn2a) in the voltage sensor module of domain II of voltage-gated sodium channels, Peptides, 68, 2015: 148–156.
5 Pan Li, Haowen Liu, Chaohua Lai, Peibei Sun, Wenping Zeng, Fangming Wu, Longhua Zhang, Sheng Wang*, Changlin Tian & Jiuping Ding. Differential Modulations of KCNQ1 by Auxiliary Proteins KCNE1 and KCNE2, Scientific Reports. 4, 2014:4973
6 HaoWen Liu, PanPan Hou, XiYing Guo, ZhiWen Zhao, Bin Hu, Xia Li, LuYang Wang, JiuPing Ding, and Sheng Wang*. Structural Basis for Calcium and Magnesium Regulation of a Large Conductance Calcium-activated Potassium Channel with β1 Subunits, J Biol, Chem, 289, 2014: 16914-16923.
7 Panpan Hou, Wenping Zeng, Geliang Gan, Caixia Lv, Xiying Guo, Zheng Zhang, Haowen Liu, Ying Wu, Jing Yao, Aguan D. Wei, Sheng Wang*, Jiuping Ding. Inter-α/β subunits coupling mediating pre-inactivation and augmented activation of BKCa(β2) Scientific Reports, 3, 2013: 1666.

联系方式
联系电话： 027-87792350
Email： shengwang@hust.edu.cn